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PaperSummary - Subgraph Centrality in Complex Networks

Subgraph Centrality in Complex Networks

Abstract ๋ฒˆ์—ญ

We introduce a new centrality measure that characterizes the participation of each node in all subgraphs in a network.

  • ์šฐ๋ฆฌ๋Š”, ๋„คํŠธ์›Œํฌ ๋‚ด์˜ ๋ชจ๋“  subgraph์— ๋Œ€ํ•ด์„œ, ๊ฐ node๊ฐ€ ์–ผ๋งˆ๋‚˜ ์ฐธ์—ฌํ•˜๋Š”์ง€๋ฅผ ํŠน์„ฑํ™”ํ•˜๋Š”, subgraph-centrality๋ฅผ ์†Œ๊ฐœํ•œ๋‹ค.

Smaller subgraphs are given more weight than larger ones, which makes this measure appropriate for characterizing network motifs.

  • ์ž‘์€ subgraph์ผ์ˆ˜๋ก, ํฐ subgraph์— ๋น„ํ•ด์„œ ํฐ weight๋ฅผ ์ฃผ๊ฒŒ ๋˜๋Š”๋ฐ, ์ด๋Š” Network motif๋ฅผ ํŠน์„ฑํ™”ํ•˜๊ธฐ ์œ„ํ•จ์ด๋‹ค.
  • Network motif๋Š” โ€œ๋ฐ˜๋ณต์ ์œผ๋กœ ๋‚˜ํƒ€๋‚˜๋Š” ๋„คํŠธ์›Œํฌ์˜ ํŒจํ„ดโ€์„ ๋งํ•ฉ๋‹ˆ๋‹ค. vertex์— ๋Œ€ํ•ด์„œ๋„ ์กด์žฌํ•  ์ˆ˜ ์žˆ์ง€๋งŒ, subgraph๊ฐ„์—์„œ๋„ ์กด์žฌํ•  ์ˆ˜ ์žˆ์ฃ . ์ด ๋ถ€๋ถ„์€ ๊ธ€๋กœ ๋ณด๋Š” ๊ฒƒ๋ณด๋‹ค, Well-Established_Motifs_and_Their_Functions ๋ถ€๋ถ„์„ ์ฝ์–ด๋ณด์‹œ๋ฉด ๋” ๋ช…ํ™•ํ•ฉ๋‹ˆ๋‹ค. ์˜ˆ๋ฅผ ๋“ค์–ด โ€œFeed-forward loops (FFL)โ€, โ€œPositive auto-regulation (PAR)โ€ ๋“ฑ์ด ์žˆ์ฃ .

We show that the subgraph centrality (SC) can be obtained mathematically from the spectra of the adjacency matrix of the network. This measure is better able to discriminate the nodes of a network than alternate measures such as degree, closeness, betweenness and eigenvector centralities.

  • ์šฐ๋ฆฌ๋Š”, subgraph centrality๊ฐ€ network์˜ adjacency matrix์—์„œ ์ˆ˜ํ•™์ ์œผ๋กœ ํš๋“๋  ์ˆ˜ ์žˆ์Œ์„ ๋ณด์—ฌ์ค„ ๊ฒƒ์ด๊ณ , ์ด ์ธก์ • ์ง€ํ‘œ๊ฐ€ ๋„คํŠธ์›Œํฌ์˜ ๋…ธ๋“œ๋ฅผ ๊ตฌ๋ถ„ํ•˜๊ธฐ ์œ„ํ•ด degree/closeness/beteenness/eigenvector cetranlity์˜ ๋Œ€์•ˆ์ด ๋  ์ˆ˜ ์žˆ์„ ๊ฒƒ์ด๋‹ค.

We study eight real-world networks for which SC displays useful and desirable properties, such as clear ranking of nodes and scale-free characteristics. Compared with the number of links per node, the ranking introduced by SC (for the nodes in the protein interaction network of S. cereviciae) is more highly correlated with the lethality of individual proteins removed from the proteome.

  • ์šฐ๋ฆฌ๋Š” 8๊ฐœ์˜ ์‹ค ์„ธ๊ณ„์˜ Subgraph Centrality๊ฐ€ ์ž˜ ์ž‘๋™ํ•˜๋Š”, scale-free ํŠน์„ฑ์„ ๊ฐ–์ถ˜ ์‹ค์ œ ์„ธ๊ณ„์˜ 8๊ฐœ์˜ real-world network๋ฅผ ๋Œ€์ƒ์œผ๋กœ ์กฐ์‚ฌํ•˜์˜€๊ณ , degree(links per node)์™€ ๋น„๊ตํ•ด๋ดค์„ ๋•Œ, subgraph centrality๊ฐ€ ๋” (๋‹จ๋ฐฑ์ฒด์—์„œ ์ œ๊ณ ๋˜๋Š” ๊ฐœ๊ฐœ์ธ์˜ ๋‹จ๋ฐฑ์งˆ)์— ๋Œ€ํ•ด correlation์ด ๋†’๋‹ค๋Š” ๊ฒƒ์„ ๋ฐœ๊ฒฌํ•˜์˜€๋‹ค.

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๊ธ€ ์ฃผ์†Œ๊ฐ€ ํด๋ฆฝ๋ณด๋“œ์— ๋ณต์‚ฌ๋˜์—ˆ์Šต๋‹ˆ๋‹ค.